Drug Toxicity Signature Generation Center

The DToxS Center has generated molecular signatures related to adverse events associated with FDA approved drugs. The molecular signatures were obtained from primary cardiomyocyte-like heart cells as well as from cardiomyocytes differentiated in vitro from induced pluripotent stem cells that were generated from fibroblasts obtained from forty male and female subjects who had passed a rigorous clinical health examination to establish that they were healthy.

The DToxS Center was supported by the NIH Common Fund LINCS Program
All Data is freely available